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Writer's pictureDr. Isabelle Amigues

Understanding Enthesitis: Causes, Diagnosis, and Treatment:

Enthesitis is a condition characterized by inflammation at the site where tendons or ligaments attach to bone, known as the enthesis. This inflammation is often associated with spondyloarthropathies, a group of inflammatory diseases that include ankylosing spondylitis and psoriatic arthritis.


Recognizing Enthesitis


If you suffer from conditions like ankylosing spondylitis or psoriatic arthritis, you might develop enthesitis. Common symptoms include pain in the heel, Achilles tendon, or the plantar fascia (the tissue along the bottom of your foot). Sometimes, enthesitis can also affect the knee, specifically at the tendon insertion points. Unlike general tendon issues often attributed to physical activity, enthesitis is specifically related to inflammation at the enthesis, which can be identified through clinical examination or ultrasound imaging. Ultrasound is particularly useful as it allows healthcare providers to visualize the inflammation, providing a clearer diagnosis.


Treating Enthesitis


Treating enthesitis involves a stepwise approach that aims to reduce inflammation and manage symptoms. Here's a breakdown of the treatment options:


  • NSAIDs (Non-Steroidal Anti-Inflammatory Drugs):

The first line of treatment often involves NSAIDs like ibuprofen, meloxicam, or  diclofenac. These medications can effectively reduce inflammation and pain in many cases of enthesitis.


  • Steroid Injections:

While steroid injections are an option, they are generally not preferred for enthesitis. Injecting steroids at the site of inflammation can potentially cause tendon rupture, making it a less desirable treatment option. Steroid injections are typically reserved for cases where other treatments have failed.


  • Biologic Therapy (TNF Inhibitors):

If NSAIDs are insufficient, the next step involves biologic therapies, specifically TNF inhibitors like Humira. These medications target specific pathways in the immune system to reduce inflammation. TNF inhibitors are often very effective in treating enthesitis and are preferred over older medications like methotrexate, sulfasalazine, and leflunomide, which have been shown to be less effective for this condition.


Ongoing Management:


If a TNF inhibitor doesn’t work, switching to another biologic may be necessary. It's essential to monitor the disease closely, as enthesitis is often a sign of ongoing, active inflammation elsewhere in the body. Addressing enthesitis effectively usually requires a comprehensive approach to managing the underlying disease.


Conclusion: 


Enthesitis is more than just tendon pain; it's a sign of an underlying inflammatory condition that needs proper diagnosis and treatment. By understanding the symptoms and following a structured treatment plan, including the use of NSAIDs, and biologics, and considering steroid injections when necessary, you can effectively manage enthesitis and improve your overall quality of life.


Are you in need of a compassionate rheumatologist who will listen and work with you toward disease remission? If you're searching for the best rheumatologist in Denver, UnabridgedMD is here for you. Click here to get in touch https://www.unabridgedmd.com or call 303-731-4006


#Enthesitis and #Inflammation are often linked with #Spondyloarthropathies such as #AnkylosingSpondylitis and #PsoriaticArthritis. Understanding these conditions is crucial for effective #Rheumatology care. For those managing #JointHealth and #ChronicPain, #BiologicTherapy, particularly #TNFInhibitors, can make a significant difference. If you're searching for a #RheumatologistDenver, look no further than #UnabridgedMD. We specialize in treating #AutoimmuneDisease and offer comprehensive #PainManagement and #PatientCare. Discover quality #HealthcareDenver with us.



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