Sleep & Autoimmunity: The Healing Connection
- Dr. Isabelle Amigues
- Apr 15
- 4 min read
Updated: Apr 17
Let’s discuss something that affects nearly every aspect of health—sleep—and its connection to autoimmune disorders. This topic is both exciting and deeply personal because sleep plays a crucial role in how the body heals and functions, particularly when managing chronic inflammation.
There was a recent stretch of poor sleep. It wasn't consistent—sometimes heading to bed super early from exhaustion and waking up in the middle of the night, other times staying up too late. And then the body started speaking up: joint pain crept in, and even a cold made an unexpected appearance. That’s rare, and it was a wake-up call to go back to the basics. One of the core pillars of health—sleep—was off.
When something feels off, it's a great time to pause and ask: am I giving the body what it needs to thrive? In this case, sleep was the missing piece. Once that was addressed, the joint pain and lingering cold symptoms vanished. It was amazing how quickly things turned around.
But it's not always just one thing. Sometimes it's sleep, stress, nutrition, movement, or perhaps an underlying infection. Bodies are complex, and health is a puzzle.
So, let's dive deeper into why sleep is such a powerful tool in managing autoimmune disorders.
The Critical Role of Sleep
A highly recommended book is Why We Sleep by Dr. Matthew Walker (that’s the name!). It’s brilliantly written, packed with science, and surprisingly funny. Fun fact: it’s also a great audiobook to fall asleep to—an outcome the author himself would be thrilled about! The message is clear: sleep matters more than we often realize.
One beautiful idea from the book is that our internal clocks vary—some are early birds, others are night owls—and that’s perfectly natural. But no matter the rhythm, everyone needs good quality sleep.
When sleep is disrupted—whether by stress, alcohol, screen time, or caffeine—inflammatory cytokines increase, that means inflammation rises, which can worsen or even contribute to autoimmune disorders. And here's the kicker: autoimmune disorders themselves can cause poor sleep. So, it becomes a vicious cycle.
Sleep Is How the Body Heals
Sleep is a time when the parasympathetic nervous system (aka the “rest and digest” system) takes over. It's the opposite of the stress-driven adrenergic system (“fight or flight”). When the body is stuck in a stress response, healing is nearly impossible.
It makes sense, right? If the body thinks there’s danger around the corner, the last thing it's going to prioritize is healing.
That’s why mindfulness techniques are often recommended alongside medical treatments—because healing isn’t just physical, it’s also nervous-system-deep. Grandmothers were right: when you're sick, sleep.
Inflammation, Fatigue & the Sleep Cycle
For many living with autoimmune disorders, fatigue is the most stubborn symptom. Even when pain and inflammation are controlled, that lingering exhaustion sticks around. Often, that’s a sign the quality of sleep is poor.
Sometimes it’s because of lifestyle habits—late-night work, screen time, or alcohol. Other times, it's pain or discomfort disrupting deep sleep. Either way, poor sleep increases inflammation, and increased inflammation disrupts sleep.
So, how do we break that cycle?
In rheumatology care, the focus is on helping reduce inflammation and achieve remission. That can relieve symptoms like pain and fatigue, making it easier for the body to return to restful sleep. But there’s another side too: what can you do at home to support that healing?
Practical Tips for Better Sleep (and Less Inflammation)
Here are some key lifestyle tweaks that can support better sleep and better health overall:
Watch the caffeine: If insomnia is an issue, try cutting off caffeine by 11 AM (or noon at the latest). That includes coffee, tea, soda, and energy drinks.
Screen-free evenings: Blue light from screens can disrupt melatonin. Try turning off devices an hour before bed. If screens are a must, blue-light-blocking glasses may help (though it’s easy to forget to wear them!).
Create a wind-down ritual: Reading a book (Why We Sleep is a great choice—or Made for More 2, a new Amazon bestseller co-authored by a certain rheumatologist 😉), taking a warm bath, journaling, or meditating can help cue the body for sleep.
Honor the body’s cues: If the body is asking for rest, honor that. There’s power in listening to internal signals instead of pushing through.
Protect sleep like it’s sacred: For example, attending a concert where the headliner comes on at midnight might not be worth sacrificing quality sleep. It's okay to leave early. The body’s needs come first.
The Big Picture
Sleep isn't just about feeling rested—it's about supporting the immune system, reducing inflammation, and healing. While poor sleep can worsen autoimmune symptoms, good sleep can help the body break out of the cycle of flares and fatigue.
This isn’t about fear, it's about empowerment. Small changes can lead to big shifts in how the body feels and functions. Everyone deserves to feel better, and sleep is one of the most powerful tools to get there.
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